Mexico solidified its position as the United States’ largest trading partner for the third consecutive year in 2025, with bilateral commerce reaching an unprecedented $872.83 billion. This represents a 3.9% increase from the $840 billion recorded in 2024, according to a WorldCity analysis of U.S. Census Bureau data. This achievement marks the second consecutive year the U.S. has recorded its highest annual trade total with any single nation. Canada ranked second, with its trade with the U.S. totaling $712.76 billion, a decrease of 6.36% from $761.2 billion in 2024. China fell to third place, experiencing a significant 28.81% year-over-year drop in trade with the U.S., totaling $414.69 billion compared to $582.49 billion in 2024. The robust growth in U.S.-Mexico trade continues to drive freight flows towards the southern border, with the Port of Entry in Laredo, Texas, remaining the busiest inland port in the U.S. This new record follows a historic 2024, when U.S.-Mexico trade first surpassed the $800 billion mark. Port Laredo continues to be the epicenter of cross-border trade, handling $354 billion in two-way trade in 2025, up from $339 billion in 2024. In December alone, Port Laredo processed $27.03 billion in trade.